In this article we will discuss about:- 1. Subject-Matter of Transgenic Mice 2. Production of Transgenic Mice 3. Uses of Transgenic Mice. Subject-Matter of Transgenic Mice: The ability to insert an exogenous (or foreign) gene into the mouse genome by direct injection into the pronuclei of zygotes was achieved just two decades ago. The term […]
Transgenic Mice: Subject Matter, Production and Uses | Biotechnology
Notes on Gene Targeting Procedures | Biotechnology
The below mentioned article provides notes on gene targeting procedures in biological process. A mutational approach has proved to be invaluable to investigators examining the roles of gene products in complex biological processes within prokaryotic and cultured eukaryotic cells. Recently it has become possible to apply this approach to a mammalian system. Gene targeting procedures […]
2 Types of Mutation Strategies | Biotechnology
The following points highlight the two types of mutation strategies. The Strategies are: 1. Cell Type-Specific Mutation Strategies 2. Inducible Mutation Strategies. 1. Cell Type-Specific Mutation Strategies: When a null mutation of a gene results in a mutant phenotype, limitations in the interpretation of that phenotype can arise because the gene is inactivated in every […]