The following points highlight the ten main characteristics of microbes.
Microbe Characteristic # 1:
The organism must be able to grow in a simple medium and should preferably not require growth factors (i.e., pre-formed vitamins, nucleotides, and acids) outside those which may be present in the industrial medium in which it is grown.
Microbe Characteristic # 2:
The organism should be able to grow vigorously and rapidly in the medium in use. A slow growing organism no matter how efficient it is, in terms of the production of the target material, could be a liability.
Microbe Characteristic # 3:
Not only should the organism grow rapidly, but it should also produce the desired materials, whether they be cells or metabolic products, in as short a time as possible, for reasons given above.
Microbe Characteristic # 4:
Its end products should not include toxic and other undesirable materials especially if these end products are for internal consumption.
Microbe Characteristic # 5:
The organism should have a reasonable genetic, and hence physiological stability.
Microbe Characteristic # 6:
The organism should lend itself to a suitable method of product harvest at the end of the fermentation.
Microbe Characteristic # 7:
Wherever possible, organisms which have physiological requirements and protect them against competition from contaminants should be used.
Microbe Characteristic # 8:
The organism should be reasonably resistant to predators such as Bdellovibrio spp or bacteriophages.
Microbe Characteristic # 9:
Where practicable the organism should not be too highly demanding of oxygen as aeration (through greater power demand for agitation of the fermentor impellers, forced air injection, etc.) contributes about 20% of the cost of the finished product.
Microbe Characteristic # 10:
Lastly, the organism should be fairly easily amenable to genetic manipulation to enable the establishment of strains with more acceptable properties.